Distinguish 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) together with all 4 canonical bases to measure multiple modes of biology from a single 5ng DNA sample, in a single experiment, with high accuracy. Identify novel multimodal biomarkers to gain transformative insights into current and future states of disease.
Here are the relevant biomodal resources for information. Find poster presentation information, case studies, interviews, and more.
Discover how alterations in DNA methylation play a crucial role in cancer research via gene expression changes and mutation occurrence. Learn more.
Professor Ellen Heitzer’s lab at the Medical University of Graz analysed eight samples from localised PCa, metastatic PCa, and suspicious Pca (men with elevated serum PSA and/or suspect digital rectal examination but negative biopsy) using the duet multiomics solution evoC.
To address the difficulties of analysing methylation data, this poster presents modality, an efficient and scalable analysis package for 5- and 6-base genomes.
Discover how new technology in next generation sequencing can capture the standard A, C, G, T bases plus epigenetic information in a single workflow.
The Aparicio lab at the British Columbia Cancer Research Centre (BCCRC) utilises 5-letter sequencing technology, duet multiomics solution +modC, to investigate ‘epigenetic rewiring’ in breast cancer cells.
