DNA methylation in Alzheimer’s Disease
DNA methylation as a mechanism, biomarker, and potential therapeutic target for Alzheimer’s disease.
Investigating the link between loss of epigenetic information and ageing
In a recent paper published in Cell, researchers from Harvard Medical School investigated if loss of epigenetic information was a cause of ageing. To do this, they developed a mouse model that enabled the investigation of DNA damage mechanisms, particularly double strand breaks, without inducing additional mutations previously linked to ageing. Mice that had induced […]
Cancer: How DNA methylation will become a powerful tool for diagnosis and prognosis
In this article, we highlight three recent studies that showcase the power of methylation screening for the diagnosis and prognostic measurement of different types of cancers. Diagnosing cancer early significantly increases the chance of survival. It allows treatment to begin before the progression or spread of the disease has accelerated, when treatment success rate is […]