Resources
Resource types
- Blog post
5hmC is far more than just a transient step in the DNA demethylation pathway as it has broad implications for gene regulation, cellular differentiation, brain function, genome stability, and disease.
- Blog post
Understanding how alterations in CpG island methylation contribute to disease states, including cancer, may provide novel targets for treatment.
- Blog post
Heterochromatin is a condensed form of chromatin that plays an essential role in maintaining genomic stability. Disruptions in its formation can lead to disease. We explore the mysteries of heterochromatin and its vital role in genome organisation.
- News article
biomodal has just announced it has filed a lawsuit against New England Biolabs in the United States District Court for the District of Massachusetts.
- Poster
Liquid biopsy for profiling of cell free DNA (cfDNA) in blood holds huge promise to transform how we experience and manage cancer by early detection and identification of residual disease and subtype.
- Poster
Formalin-fixed, paraffin-embedded (FFPE) specimens are commonly used for long-term storage in research and clinical settings, including immunohistochemistry, oncology, and genomics.
- Technical note
DNA contains molecular information encoded in both genetic and epigenetic bases, essential for understanding biology.
- Poster
Using the 6‑base genome, genetics, 5mC and 5hmC, to gain multimodal insights into genome organisation and gene regulation
- Poster
To address the difficulties of analysing methylation data, we present modality, an efficient and scalable analysis package for 5- and 6-base genomes.
- Blog post
An Epigenome Wide Association Study (EWAS) investigates the relationship between epigenetic modifications and traits/diseases. Learn why they are important.
- Webinar
Join Dr Emily Hodges, assistant professor of biochemistry at Vanderbilt University, to learn more about how the Hodges Lab utilises 6-base genome to investigate the dynamics of enhancer DNA methylation during cellular differentiation.
