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DNA contains molecular information encoded in both genetic and epigenetic bases, essential for understanding biology.
Liquid biopsy for profiling of cell free DNA (cfDNA) in blood holds huge promise to transform how we experience and manage cancer by early detection and identification of residual disease and subtype.
Formalin-fixed, paraffin-embedded (FFPE) specimens are commonly used for long-term storage in research and clinical settings, including immunohistochemistry, oncology, and genomics.
Using the 6‑base genome, genetics, 5mC and 5hmC, to gain multimodal insights into genome organisation and gene regulation
To address the difficulties of analysing methylation data, we present modality, an efficient and scalable analysis package for 5- and 6-base genomes.
An Epigenome Wide Association Study (EWAS) investigates the relationship between epigenetic modifications and traits/diseases. Learn why they are important.
Join Dr Emily Hodges, assistant professor of biochemistry at Vanderbilt University, to learn more about how the Hodges Lab utilises 6-base genome to investigate the dynamics of enhancer DNA methylation during cellular differentiation.
Formalin-Fixed Paraffin-Embedded (FFPE) tissue plays a critical role in histopathological diagnosis, and it is particularly valuable in the diagnosis of diseases like cancer.
FFPE cancer samples are an incredibly important and clinically relevant information source for directly studying the causes and consequences of the disease. This technical note shows how duet evoC can identify DNA methylation markers from FFPE samples.
Liquid biopsy for profiling of cell free DNA (cfDNA) in blood holds huge promise to transform how we experience and manage. But can you get More information from limited DNA: simultaneous measurement of genetics, 5hmC and 5mC in cell-free DNA?
The combinatorial power of genetics and epigenetics is vital to understanding biology in healthy and cancerous states.
The 6-base genome expands our understanding of genetics by incorporating both genetic & epigenetic data to get a clearer picture of health and disease biology.
Cambridge Epigenetix is now biomodal