Resources
Resource types
- Poster
The combination of PARPi (Talazoparib – TAL) and DNMTi (Decitabine – DAC) functions synergistically to inhibit PCa cell lines and patient-derived PTOs.
- Product sheet
Ihr duet multiomics solution evoC-Produktblatt finden Sie hier
- Poster
Circulating tumor DNA (ctDNA) purity can be used to predict therapy response of metastatic castration-resistant prostate cancer (mCRPC) to PD-L1/PARP1 inhibition.
- Webinar
By employing the 6-base genome via duet evoC, we have identified differentially methylated genes that may be responsible for therapy resistance and tumor aggression in pancreatic cancer.
- News article
Alfonso Bellacosa, MD, PhD, a Professor in the Nuclear Dynamics and Cancer Research Program and Johnathan R. Whetstine, PhD, the Jack Schultz Chair in Basic Science, both at Fox Chase.
- Blog post
Most transposable elements (TE) lay dormant, buried under repressive epigenetic marks that ensure their influence over cell behaviour remains minimal. When they awaken, however, the consequences can be far reaching.
- Poster
Professor Ellen Heitzer’s lab at the Medical University of Graz analysed eight samples from localised PCa, metastatic PCa, and suspicious Pca (men with elevated serum PSA and/or suspect digital rectal examination but negative biopsy) using the duet multiomics solution evoC.
- Publication
Exciting news, Professor Anjana Rao’s lab at La Jolla Institute for Immunology has published a new study with Nature Structural & Molecular Biology. Learn how 6-base sequencing can reveal early biomarkers of genome dysfunction.
- Publication
Assistant Professor Emily Hodges' lab at Vanderbilt University used differentiating neural stem cells as a model system to understand the relationship between DNA methylation and genome dynamics.
- Publication
Learn how Associate Professor Alex Bick's lab at Vanderbilt University Medical Center conducted a multiracial meta-analysis of epigenome-wide association studies (EWAS) of Clonal Hematopoiesis of Indeterminate Potential (CHIP).
- News article
As well as helping researchers identify tumour DNA amid the soup of regular cell-free DNA, the fact that different tissues have distinct methylation patterns can help explain where the cell-free DNA might be coming from. “There are many advantages to being able to study epigenomics in concert with genomic features,” says Dawson.
