Resources
Resource types
- Poster
DNA comprises molecular information stored in genetic and epigenetic bases, both of which are vital to our understanding of biology. In human genomes, an epigenetic modification at the fifth carbon of cytosines bases comprises one fundamental pathway by which genes can be silenced or activated.
- Poster
DNA comprises molecular information stored in genetic and epigenetic bases, both of which are vital to our understanding of biology. The interplay between genetics and the DNA epigenome orchestrates complex biological phenomena as diverse as cell fate, ageing, the response to environmental stimuli, and disease pathogenesis.
- Product sheet
Novel single-base-resolution solution that delivers the standard four-base sequencing (A, C, G, and T), and distinguishes between 5‑methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC), on the same DNA molecule.
- Product sheet
duet multiomics solution +modC provides complete genetic and modified cytosine (modC) information from a single low volume DNA sample. Read the product sheet.
- Blog post
Epigenetics, a captivating field of study, has revolutionised our understanding of gene regulation.
- Blog post
DNA stores multimodal information through a process known as DNA methylation and it plays a crucial role in gene expression and regulation.
- Blog post
Next generation sequencing technologies only capture four letters in their readout, the canonical bases A, T, C, and G, however new technology can now capture epigenetic data also.
- Webinar
In this Teach me in 10 episode we will explore how simultaneous sequencing of genetic and epigenetic bases in cfDNA allows for early cancer detection.
- Technical note
Enrichment protocols enable deep interrogation of target areas whilst maintaining cost effectiveness. Two enrichment methods performed with the duet multiomics solution +modC are presented here.
- Blog post
DNA methylation as a mechanism, biomarker, and potential therapeutic target for Alzheimer's disease.
