Resources
Resource types
- News article
As well as helping researchers identify tumour DNA amid the soup of regular cell-free DNA, the fact that different tissues have distinct methylation patterns can help explain where the cell-free DNA might be coming from. “There are many advantages to being able to study epigenomics in concert with genomic features,” says Dawson.
- Poster
To address the difficulties of analysing methylation data, this poster presents modality, an efficient and scalable analysis package for 5- and 6-base genomes.
- Poster
This poster demonstrates that the combination of 5mC and 5hmC is highly effective for early-stage CRC detection in cfDNA - read it now.
- Blog post
Understanding the factors that affect DNA methylation can open up new avenues to explore human health and disease.
- Blog post
Deoxyribonucleic acid, or DNA, is the fundamental building block of life. Let's explore the fascinating types of DNA in the world.
- Webinar
Robert Osborne, PhD, Senior Vice President of Research & Development provides a high-level overview of biomodal’s bioRXiv preprint, 5mC and 5hmC are synergistic biomarkers for early detection of colorectal cancer.
- Blog post
Liquid biopsy represents a groundbreaking advancement in disease diagnostics, offering a less invasive alternative to traditional tissue biopsies, particularly for cancer.
- News article
Our study investigates the roles of 5‑methylcytosine (5mC) and 5‑hydroxymethylcytosine (5hmC) as biomarkers for early-stage colorectal cancer (CRC) detection in cell-free DNA (cfDNA).
- Blog post
The utilisation of genetic biomarkers in liquid biopsy has caused a revolution in cancer diagnostics and personalised medicine.
- Poster
Here we show that the combination of resolved methylation and genomic data combined with machine-learning can generate accurate inference of gene expression (both steady-state and nascent), chromatin accessibility, and enhancer state, demonstrating the key role of 5mC and 5hmC in gene regulation.
