One solution, exponential insight

Finally see it all

Uncover the biomarkers you’re searching for with a single workflow solution. biomodal’s multiomic analysis provides both genetic and epigenetic data simultaneously with groundbreaking clarity, precision and speed.

Genetics alone does not tell the whole story

Understanding both genetics and epigenetics with a multiomic approach can provide valuable insight into the dynamic state of a cell. Epigenetic modification of cytosine is a crucial pathway in the regulation of gene expression.

duet multiomics solution evoC

A true 6-base genome enabling the measurement of both 5‑methylcytosine (5mC) and 5‑hydroxymethylcytosine (5hmC).

duet multiomics solution +modC​

This approach provides the most efficient way to obtain genetic and methylation information simultaneously.

Move beyond a 4-base genome

Our single workflow solution provides the most efficient way to obtain genetic and methylation information simultaneously from a single sample using your existing next-generation sequencing pipeline

biomodal duet multiomics solution workflow

Conventional methods: multiple samples, multiple workflows, multiple data analyses

These approaches require splitting the sample and running parallel workflows, with multiple data analyses and significant information loss.

Conventional workflow

A single comprehensive workflow to uncover the DNA modifications that matter

Simultaneous sequencing of genetic and epigenetic bases in DNA

Reveal more genetic data, all at once

High accuracy reads

The duet multiomic solution inherently suppresses PCR and sequencing errors with a base call accuracy in excess of Q40.

Seamless integration

Supercharge your genetic insights without costly in-house bioinformatics or changing your current sequencing platform.

Optimised bioinformatics

Precise sequence information in one run, eliminating the inaccuracy of inferred methylation as well as data loss from merged sequencing workflows.

Discover the full story of genetic and epigenetic change

Variant-associated methylation (VAM)

Acquiring genetic and methylation data simultaneously produces higher quality calls that show how methylation promotes or silences specific genes causing deregulation, altered expression, or potential disease.

Liquid biopsy

Maximise the genetic data you obtain from cell-free DNA (cfDNA) with our combined workflow, allowing you to use precious low input DNA samples to detect and monitor disease states.

Applications for multiomics discovery

Cancer research

Cancer research

Multiomics analysis offers a deeper understanding of the drivers of cancer. Our technology allows you to bring multiomic analysis to your research using your existing DNA sequencing infrastructure.

Neurodegenerative disease research

Neurodegenerative disease

Reveal the role of DNA methylation in the most common neurodegenerative diseases, and identify potential targets for promising therapeutics.


Liquid biopsy

Liquid biopsy

Enhance the power of your liquid biopsy sample for disease detection and monitoring, with a low-input DNA sample.



Probe and determine the markers of biological age to better understand age-related diseases including Alzheimer’s disease, osteoporosis, type II diabetes and chronic heart disease.

Precision medicine

Precision medicine​

Use multiomics analysis to identify targets for promising therapeutics tailored to the genetics and epigenetics of the individual.


Non-invasive prenatal testing (NIPT)

Combining genetic and epigenetic DNA sequencing has the potential to reduce the time taken to detect pregnancy complications and significant genetic and epigenetic variations in a foetus.


Explore our science

We can help you reveal new data and multimodal insights from your research.

Cambridge Epigenetix is now biomodal