DNA contains molecular information encoded in both genetic and epigenetic bases, essential for understanding biology. However, interrogating both of these informational layers simultaneously has traditionally been challenging. With the recent introduction of duet multiomics solution evoC, which uniquely reads genetic and epigenetic cytosine modifications, this challenge has been overcome.

Using Unique Molecular Identifiers (UMIs) for sequencing enhances the accuracy of genome interrogation, whether examining the whole genome or specific regions with a target enrichment panel. This method increases the number of unique reads, reducing both sequencing requirements and costs