Visit biomodal at booth
Explore NextGen Omics 2024: Unlocking Future Insights in Multi-Omics Research
Join 700+ leaders, experts and researchers at our flagship NextGen Omics 2024, featuring the 16th Annual NGS & Clinical Diagnostics Congress, 12th Annual Single Cell & Spatial Analysis Congress and 6th Annual Digital PCR & Liquid Biopsies Congress and CRISPR-Based Medicine Congress
MBPhD Student
University College London (UCL) and The Francis Crick Institute
Using biomodal’s duet multiomics solution evoC, we examined 5mC and 5hmC methylation marks in postmortem brain tissue from individuals with Parkinson’s disease and controls. Our study reveals disease-specific alterations in methylation patterns, observed at both the genome-wide and gene-specific levels. We also analysed the methylation signatures of genes known to be associated with Parkinson’s disease. This work offers comprehensive insights into the epigenetic mechanisms underlying Parkinson’s disease.
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Novel single-base-resolution solution that delivers the standard four-base sequencing (A, C, G, and T), and distinguishes between 5‑methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC), on the same DNA molecule.
