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duet multiomics solution evoC

Unlock the power of the 6-base genome with duet evoC data, providing unprecedented insight, including A, C, G, T plus 5mC and 5hmC, in a single read. Learn more

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A high-performance toolkit for large-scale analysis of 5- and 6-base genomes

To address the difficulties of analysing methylation data, this poster presents modality, an efficient and scalable analysis package for 5- and 6-base genomes.

Inferring genome organisation and gene regulation from 6-base sequencing data

Here we show that the combination of resolved methylation and genomic data combined with machine-learning can generate accurate inference of gene expression (both steady-state and nascent), chromatin accessibility, and enhancer state, demonstrating the key role of 5mC and 5hmC in gene regulation.

Measuring genetics, 5mC and 5hmC at single-base resolution

Using the 6‑base genome, genetics, 5mC and 5hmC, to gain multimodal insights into genome organisation and gene regulation

biomodal delivers the 6-base genome with a powerful new multiomic solution, duet evoC

Novel solution – duet evoC – distinguishes 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) revealing unprecedented insights into current and future states of disease using one 5ng DNA sample

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One sample. One workflow. One solution.

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Christine Hipsky

Thao Huynh

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