From global methylation patterns to differentially methylated regions, high-resolution data can help you get more from your studies.
Among the most studied epigenetic marks are 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC). Though only a hydroxyl group apart, these two modifications have distinct biological roles and implications. Having the ability to resolve between them opens new possibilities in the study of development, disease, and cellular identity.