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duet multiomics solution evoC

Unlock the power of the 6-base genome with duet evoC data, providing unprecedented insight, including A, C, G, T plus 5mC and 5hmC, in a single read. Learn more

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A high-performance toolkit for large-scale analysis of 5- and 6-base genomes

To address the difficulties of analysing methylation data, this poster presents modality, an efficient and scalable analysis package for 5- and 6-base genomes.

Inferring genome organisation and gene regulation from 6-base sequencing data

Here we show that the combination of resolved methylation and genomic data combined with machine-learning can generate accurate inference of gene expression (both steady-state and nascent), chromatin accessibility, and enhancer state, demonstrating the key role of 5mC and 5hmC in gene regulation.

biomodal delivers the 6-base genome with a powerful new multiomic solution, duet evoC

Novel solution – duet evoC – distinguishes 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) revealing unprecedented insights into current and future states of disease using one 5ng DNA sample

Deep, targeted simultaneous sequencing of genetics and epigenetics in DNA

DNA comprises molecular information stored in genetic and epigenetic bases, both of which are vital to our understanding of biology. The interplay between genetics and the DNA epigenome orchestrates complex biological phenomena as diverse as cell fate, ageing, the response to environmental stimuli, and disease pathogenesis.

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Second Annual New York City Chromatin Club Symposium

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One sample. One workflow. One solution.

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Craig Fishman

Mark Consugar

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