biomodal is a proud sponsor of the Boston Epigenetic Society.
The Boston Epigenetic Society has been founded to:
– Promote epigenetics and epi transcriptomics
– Foster research connections between academics and industry epigenetics scientists
– Help promote new methods
– Create a support system for experimental epigenetics research
The Society brings together both academic and industry partners all sharing a passion for epigenetics.
Please REGISTER HERE for a dynamic session!
Invited Speaker: Jared Churko, Associate Professor in the Department of Cellular and Molecular Medicine, University of Arizona
Description – Bicuspid aortic valve (BAV) is the most common congenital heart defect, yet the genetic and molecular mechanisms underlying the disease remain largely unresolved. In this webinar, the speaker, Jared Churko, will trace a research path from human genetic discovery to functional interrogation in vivo, focusing on two single-nucleotide variants linked to BAV. Attendees will learn how patient sequencing studies and population-scale genetics led to the identification of variants in GATA4 and DHX38, and how targeted mouse models were used to explore their impact on cardiac development and function. The talk will highlight the use of advanced multi-omic approaches—including single-cell transcriptomics, chromatin conformation profiling, and long-read sequencing—to uncover unexpected consequences of subtle genetic changes in the heart. By integrating genomics, epigenomics, and transcriptomics, this webinar offers a compelling look at how single-nucleotide variants can reshape molecular programs and drive congenital heart disease, while raising new questions about genetic architecture, mechanism, and phenotypic diversity in BAV.
