More Insight from Every Fragment
Why Preserving Native cfDNA Features Improves Liquid Biopsy Analysis
When working with cfDNA, every fragment has the potential to contribute valuable biological insight. However, conventional library preparation methods can alter methylation signals and fragment characteristics before they are measured, limiting sensitivity for liquid biopsy applications and force you to choose between genetics, epigenetics and fragmentomics.
Join us to learn how a single-stranded ligation approach preserves the native features of cfDNA by eliminating end-repair. We'll present new data showing how improved fragment-level accuracy promises to enhance the detection of tumor-derived DNA and support more accurate tissue-of-origin analysis, helping researchers get more insight from every sample.
Related Webinars
Teach me in 10: 5mC and 5hmC are synergistic biomarkers for early detection of colorectal cancer
Robert Osborne, PhD, Senior Vice President of Research & Development provides a high-level overview of biomodal's bioRxiv preprint, 5mC and 5hmC are synergistic biomarkers for early detection of colorectal cancer.
See more
Part 1: Understanding the dynamics of enhancer DNA methylation during cellular differentiation
Join Emily Hodges, PhD, Assistant Professor of Biochemistry at Vanderbilt University, to learn more about how the Hodges Lab utilises 6-base genome to investigate the dynamics of enhancer DNA methylation during cellular differentiation.
See more
Reveal the power of the 6-base genome and explore 5mC and 5hmC in Parkinson's disease in the brain
Burleen Chhatwal from University College London, UK, will demonstrate how biomodal's 6-base genome supported the successful analysis of both 5mC and 5hmC modifications in Parkinson's disease compared to controls in a pilot study.
See moreFrom every fragment, the full picture
Maximize insight from every precious sample by using single-stranded ligation to read genetics, 5mC, 5hmC and fragmentomics from the same molecule. Ideal for cfDNA and liquid biopsy.
Learn more about duet 6-base mosaicLearn more