DNA methylation serves as a pivotal epigenetic mechanism that significantly influences gene regulation by recruiting proteins that facilitate gene repression or by hindering transcription factors
Understanding how alterations in CpG island methylation contribute to disease states, including cancer, may provide novel targets for treatment.
The study of genomic DNA (gDNA) has revolutionised the field of genetics, allowing scientists to gain a deeper understanding of how traits are inherited and how genetic variations contribute to disease.
Heterochromatin is a condensed form of chromatin that plays an essential role in maintaining genomic stability. Disruptions in its formation can lead to disease. We explore the mysteries of heterochromatin and its vital role in genome organisation.
biomodal has just announced it has filed a lawsuit against New England Biolabs in the United States District Court for the District of Massachusetts.
Formalin-fixed, paraffin-embedded (FFPE) specimens are commonly used for long-term storage in research and clinical settings, including immunohistochemistry, oncology, and genomics.
Liquid biopsy for profiling of cell free DNA (cfDNA) in blood holds huge promise to transform how we experience and manage cancer by early detection and identification of residual disease and subtype.
To address the difficulties of analysing methylation data, we present modality, an efficient and scalable analysis package for 5- and 6-base genomes.
Using the 6‑base genome, genetics, 5mC and 5hmC, to gain multimodal insights into genome organisation and gene regulation
An Epigenome Wide Association Study (EWAS) investigates the relationship between epigenetic modifications and traits/diseases. Learn why they are important.
