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Dr. Sophie Kirschner, Associate Director, Translational Medicine, Early Oncology at AstraZeneca will present data using biomodal’s 6-base multiomics sequencing solution, duet evoC.
Distinguishing 5mC and 5hmC, enabled through duet evoC and the 6-base genome, delivered an AUC of 0.95 for stage I colorectal cancer from liquid biopsy, improving the earlier detection of stage I colorectal cancer from cfDNA samples!
biomodal has debuted in the top 10 of The Sunday Times Top 100 Tech Companies 2026.
biomodal announced it has filed a lawsuit against Watchmaker Genomics (“Watchmaker”) in the US District Court for the District of Colorado.
Explore the importance of epigenetics and how it shapes health, disease, and precision medicine through gene regulation, and DNA methylation.
This study demonstrates the value of moving beyond legacy epigenetic sequencing technologies that provide a modC readout.
This poster demonstrates compatibility of duet evoC with formalin-damaged DNA including clinical FFPE samples.
Patterns of 5hmC and 5hmC provide insight into tissue-specific gene expression with the ability to better distinguish high and low expressed genes than 5mC or 5modC data.
Using modality XPLR, we reveal variation in 5mC and 5hmC levels across tissues, with a pronounced increase in 5hmC in cerebellum and concomitant decrease in 5mC.
modality XPLR is an accessible and scalable software tool designed for scientists and translational researchers to uncover disease-relevant epigenetic signatures, link methylation to gene regulation, and support biomarker discovery—empowering you to identify, classify, and monitor disease.
DMRs serve as powerful biomarkers for diagnostics, prognostics, and therapeutic response, especially in contexts like cancer, where methylation dynamics can signal early transformation or treatment efficacy.
Maja Jagodic, Professor of Neuroinflammation at Karolinska Institutet, and her research group are combining genomic and epigenomic analyses to uncover how genetics, environment, and lifestyle interact in the onset and progression of MS.

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