Measuring genetics, 5mC and 5hmC at single-base resolution
Using the 6‑base genome, genetics, 5mC and 5hmC, to gain multimodal insights into genome organisation and gene regulation
Using the 6‑base genome, genetics, 5mC and 5hmC, to gain multimodal insights into genome organisation and gene regulation
An Epigenome Wide Association Study (EWAS) investigates the relationship between epigenetic modifications and traits/diseases. Learn why they are important.
Formalin-Fixed Paraffin-Embedded (FFPE) tissue plays a critical role in histopathological diagnosis, and it is particularly valuable in the diagnosis of diseases like cancer.
Liquid biopsy for profiling of cell free DNA (cfDNA) in blood holds huge promise to transform how we experience and manage. But can you get More information from limited DNA: simultaneous measurement of genetics, 5hmC and 5mC in cell-free DNA?
The combinatorial power of genetics and epigenetics is vital to understanding biology in healthy and cancerous states.
The 6-base genome expands our understanding of genetics by incorporating both genetic & epigenetic data to get a clearer picture of health and disease biology.
We are delighted to present BaseSpace Sequence Hub data for duet multiomics solution +modC.
RNA sequencing (RNA-seq) has become immensely popular and indispensable in modern biological research. We look at the considerations and challenges of this technology.
Novel solution – duet evoC – distinguishes 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) revealing unprecedented insights into current and future states of disease using one 5ng DNA sample
DNA comprises molecular information stored in genetic and epigenetic bases, both of which are vital to our understanding of biology. The interplay between genetics and the DNA epigenome orchestrates complex biological phenomena as diverse as cell fate, ageing, the response to environmental stimuli, and disease pathogenesis.