Resources
Resource types
- Application note
Results from Professor Sarah-Jane Dawson's lab at the Peter MacCallum Cancer Centre and University of Melbourne suggest that profiling cfDNA with duet evoC would be very useful for the analysis of liquid biopsy samples to generate biologically relevant data for exploring early detection and disease progression in HCC.
- Application note
Generating multiomic data from as little as 5ng of cfDNA that can be used to identify SNPs, CNVs, differentially methylated regions (DMRs), and variant associated methylation (VAM). Using these techniques, methods to identify new potential biomarkers and fragment length profiles are also discussed.
- News article
Novel solution - duet evoC - distinguishes 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) revealing unprecedented insights into current and future states of disease using one 5ng DNA sample
- Poster
DNA comprises molecular information stored in genetic and epigenetic bases, both of which are vital to our understanding of biology. The interplay between genetics and the DNA epigenome orchestrates complex biological phenomena as diverse as cell fate, ageing, the response to environmental stimuli, and disease pathogenesis.
- Product sheet
Novel single-base-resolution solution that delivers the standard four-base sequencing (A, C, G, and T), and distinguishes between 5‑methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC), on the same DNA molecule.
- Product sheet
duet multiomics solution +modC provides complete genetic and modified cytosine (modC) information from a single low volume DNA sample. Read the product sheet.
- News article
A Q&A with Peter Fromen, CEO of biomodal, emphasising the potential applications of their technology, particularly in oncology, liquid biopsy, aging, and neurodegenerative disorders.
- Blog post
Discover how new technology in next generation sequencing can capture the standard A, C, G, T bases plus epigenetic information in a single workflow.
- Webinar
In this Teach me in 10 episode we will explore how simultaneous sequencing of genetic and epigenetic bases in cfDNA allows for early cancer detection.
- Technical note
Enrichment protocols enable deep interrogation of target areas whilst maintaining cost effectiveness. Two enrichment methods performed with the duet multiomics solution +modC are presented here.
- Webinar
Join the Boston Epigenetics Society and biomodal founder Prof. Sir Shankar Balasubramanian FRS to discuss what DNA is trying to tell us.